The besieged Damascus suburb of Darayya has received its first aid convoy since November 2012, according to the Red Cross.
UN aid officials had said the town was suffering dire shortages of food, clean water and medicine.
A 48-hour ceasefire for the town, which lies south of the Syrian capital, came into force early on Wednesday.
The UN’s humanitarian arm said vaccines, baby milk, medicine and nutritional goods were being delivered,.
In April, the UN said at least 4,000 people were besieged in Darayya by Syrian government forces.